All-natural Herbal Supplements for Better, Stronger Orgasms
300 S 2nd St, Ste 2 Surf City, NJ 08008
Mon-Fri: 09 AM - 09 PM

Published Studies, Articles, Books, and Online Resources

“Defined” Pollen Studies

Buck, A.C., R. Cox, R.W.M. Rees, L. Ebeling, and A. John.
"Treatment of Outflow Tract Obstruction Due to Benign Prostatic Hyperplasia with Pollen Extract."
British Journal of Urology. 1990. 66.

Abstract
Department of Urology, University Hospital of Wales, Cardiff.

Whilst prostatectomy remains the "gold standard" for the treatment of outflow tract obstruction due to benign prostatic hyperplasia, medical treatment--if only for symptomatic relief--appears to be an attractive alternative. Most of the pharmacological agents in use block the hormonal or the sympathetic neurological pathways that influence prostate growth and function. All of these drugs are known to have side effects. Sixty patients with outflow obstruction due to benign prostatic hyperplasia (BPH) were entered into a double-blind, placebo-controlled study to evaluate the effect of a 6-month course of the pollen extract, Cernilton. There was a statistically significant subjective improvement with Cernilton (69% of the patients) compared with placebo (30%). There was a significant decrease in residual urine in the patients treated with Cernilton and in the antero-posterior (A-P) diameter of the prostate on ultrasound. However, differences in respect of flow rate and voided volume were not statistically significant. It is concluded that Cernilton has a beneficial effect in BPH and may have a place in the treatment of patients with mild or moderate symptoms of outflow obstruction.

To retrieve the full report go to:http://www.ncbi.nlm.nih.gov/pubmed/1699628


Buck, A.C., R.W.M. Rees, and L. Ebeling.
"Treatment of Chronic Prostatitis and Prostatodynia with Pollen Extract."
British Journal of Urology, 1990.64

Abstract
Department of Urology, Leighton Hospital, Crewe.

Chronic abacterial prostatitis and prostatodynia are notoriously difficult both to diagnose and to treat. These patients tend to have received several courses of antibiotics, antiinflammatory agents or adrenergic blockade and various other therapeutic manoeuvres with little success. The pollen extract, Cernilton, is reported to be effective in the treatment of this condition and we present the results of an open trial with Cernilton in a group of 15 patients with chronic prostatitis and prostatodynia. In 13 patients there was either complete and lasting relief of symptoms or a marked improvement; 2 patients failed to respond. Cernilton was found to be effective in the treatment of chronic prostatitis and prostatodynia. Its precise mode of action is not known, although experimental studies suggest that it has anti-inflammatory and anti-androgenic properties.

To retrieve the full report go to: http://www.ncbi.nlm.nih.gov/pubmed/2692777


Clouatre, Dallas, Ph.D.
Pollen Extract for Prostate Health 1997,
San Francisco, CA: Pax Publishing.

For more info about this publication go to: Pollen Extract for Prostate Health


Elist, J.
“Effects of pollen extract preparation on lower urinary tract symptoms in patients with chronic nonbacterial prostatitis/chronic pelvic pain syndrome: A randomized, double-blind, placebo-controlled study”
(2006), 67  Urology: 60-63.

Abstract
To assess the efficacy and safety of the pollen extract preparation Prostat/Poltit in the treatment of patients with chronic nonbacterial prostatitis/chronic pelvic pain syndrome.

To retrieve the full report go to: http://linkinghub.elsevier.com/retrieve/pii/S0090429505011313


Kimura, Masayasu, I. Kimura, K. Nakase, T. Sonobe, and N. Mori,
"Micturition Activity of Pollen Extract: Contractile Effects of Bladder
and Inhibitory Effects on Urethral Smooth Muscle."

April, 1986. Planta Medica

Abstract
The contractile and inhibitory effects of pollen extracts on bladder and urethral smooth muscle strips from mice and domestic pigs were investigated. In the mice bladder strips, T-60 (a water-soluble extract), GBX (an acetone-soluble extract), and CN (consisting of both T-60 and GBX at a ratio of 20:1) induced contractions at 0.1-3.0 mg/ml in a concentration-dependent manner. CN, T-60, and GBX (3.0 mg/ml) attained 27.6, 27.0, and 7.3% of the ACh response (10.0 microg/ml). The T-60 effect was antagonized noncompetitively by atropine (0.029-0.29 ng/ml). CN, T-60, and GBX inhibited noradrenaline (NA)-contracted urethral strips of mice (IC (50) values for NA 0.3 microg/ml: 0.508, 0.553, and 0.888 mg/ml, and for NA 10.0 microg/ml : 0.556, 0.705, and 0.673 mg/ml). Only GBX relaxed the normal tone of pig urethral strips. The water-soluble extract of corn ( ZEA MAYS) pollen, the main pollen of CN, contracted the mice bladder strips and inhibited NA-contracted urethral strips of mice more potently than T-60. The acetonesoluble extract of corn pollen relaxed the normal tone of the pig urethra and inhibited the NA-contracted mouse urethra more effectively than GBX. These results indicate that by pollen extracts (mainly corn pollen extracts) the urine discharge may be caused by the contractile effect on the bladder, and its inhibitory or relaxing effect on the urethra.

To retrieve the full report go to: http://www.molecularstation.com/research/micturition-activity-of-pollen-extract-contractile-effects-on-bladder-and-inhibitory-effects-on-urethral-smooth-muscle-of-mouse-and-pig-17345220.html#abstract


Rugendorff, E.W., W. Weidner, L. Ebling, and A.C. Buck.
"Results of Treatment with Pollen Extract (Cernilton) in Chronic Prostatitis and Prostatodynia."
British Journal of Urology. 1993.71

Abstract
Department of Urology, Georg-August-University, Göttingen, Germany.

We report the results of a prospective study with the pollen extract, Cernilton N, in a dose of 1 tablet tid for 6 months for the treatment of chronic prostatitis syndrome in 90 patients. The factors documented before and after 3 and 6 months' treatment were digital rectal examination (DRE) of the prostate, uroflowmetry, bacterial studies, leucocyte counts in urine and measurement of complement C3/coeruloplasmin in the seminal fluid. The patients were divided into 2 groups: those without associated complicating factors (CFs) (n = 72) and those with complicating factors, i.e. urethral strictures, prostatic calculi, bladder neck sclerosis (n = 18). In the group without CFs, 56 (78%) had a favorable response; 26 (36%) were cured of their symptoms and signs and 30 (42%) improved significantly with an increase in flow rate, a reduction in leukocyturia in the post-prostate massage urine (VB3) and a decrease in complement C3/coeruloplasmin in the ejaculate. In the patients with CFs only 1 patient showed a response. Complicating factors should be considered in patients who fail to respond to treatment within 3 months. Cernilton N was well tolerated by 97% of patients.

To retrieve the full report go to: http://www.ncbi.nlm.nih.gov/pubmed/8499988

Eurycoma Longifolia Studies

Ang HH, Cheang HS
Effects of eurycoma longifolia jack on laevator ani muscle in both uncastrated and testosterone-stimulated castrated intact male rats.
Arch Pharm Res. 2001 Oct; 24(5):437-40.

Abstract
School of Pharmaceutical Sciences, University Science Malaysia, Minden, 11800, Penang, Malaysia.

It has been reported that Eurycoma longifolia Jack commonly known as Tongkat Ali has gained notoreity as a symbol of man's ego and strength by the Malaysian men because it increases male virility and sexual prowess during sexual activities. As such, the effects of 200, 400 and 800 mg/kg of butanol, methanol, water and chloroform fractions of E. longifolia Jack were studied on the laevator ani muscle in both uncastrated and testosterone-stimulated castrated intact male rats after dosing them for 12 consecutive weeks. Results showed that 800 mg/kg of butanol, methanol, water and chloroform fractions of E. longifolia Jack significantly increased (p<0.05) the leavator ani muscle to 58.56+/-1.22, 58.23+/-0.31, 60.21 +/-0.86 and 62.35 +/-0.98 mg/100 g body weight, respectively, when compared with the control (untreated) in the uncastrated intact male rats and 49.23+/-0.82, 52.23+/-0.36, 50.21+/-0.66 and 52.35+/-0.58 mg/100 g body weight, respectively, when compared to control (untreated) in the testosterone-stimulated castrated intact male rats. Hence, the pro-androgenic effect as shown by this study further supported the traditional use of this plant as an aphrodisiac.

To retrieve the full report go to: http://www.ncbi.nlm.nih.gov/pubmed/11693547


Ang HH, Cheang HS, Yusof AP
Effects of eurycoma longifolia Jack (Tongkat Ali) on the initiation of sexual performance of inexperienced castrated male rats.
Fundam Clin Pharmacol. 2002 Dec; 16(6):479-83, Exp Anim. 2000 Jan; 49(1):35-8.

Abstract
School of Pharmaceutical Sciences, University Science Malaysia, Minden, 11800, Penang, Malaysia

The effects of various fractions of Eurycoma longifolia Jack were studied on the orientation activities of the inbred, adult middle-aged Sprague-Dawley rats, 9 months old and retired breeders towards the receptive females (anogenital sniffing, licking, mounting), the environment (climbing, raring, exploration), themselves (nongenital grooming, genital grooming) and mobility (restricted, unrestricted) after treating these subjects twice daily for 10 days. Results showed that subjects treated with 800 mg/kg of E. longifolia Jack increased orientation activities towards the receptive females (anogenital sniffing, licking and mounting), increased genital grooming towards themselves and restricted movements to a particular area of the cage but decreased interest in the external environment (climbing, raring, exploration) as compared with the controls during the investigation period. In conclusion, this study gives further evidences that different fractions of E. longifolia Jack modified the orientation activities of the middle-aged male rats.

To retrieve the full report go to: http://www.ncbi.nlm.nih.gov/pubmed/12685506


Jack. Ang HH, Ngai TH.
Aphrodisiac evaluation in non-copulator male rats after chronic administration of Eurycoma longifolia
Fundam Clin Pharmacol.  2001 Aug;15(4):265-8

Abstract
School of Pharmaceutical Sciences, University of Science Malaysia, Minden, 11800, Penang, Malaysia.

The aphrodisiac effect of Eurycoma longifolia Jack (0.5 g/kg) was evaluated in noncopulator male rats using an electrical cage. Fractions of E. longifolia Jack decreased the hesitation time of noncopulator male rats, throughout the investigation period. Furthermore, it possessed a transient increase in the percentage of the male rats responding to the right choice, more than 50% of the male rats scored "right choice" after 3 weeks post-treatment and the effect became more prominent after 8 weeks post-treatment (only 40-50% of the control male rats responded to the right choice) using the electrical copulation cage. Hence, this study lends further support to the use of the plant by indigenous populations as a traditional medicine for its aphrodisiac property.

To retrieve the full report go to: http://www.ncbi.nlm.nih.gov/pubmed/11564133


Ang HH, Lee KL, Kiyoshi M.
Eurycoma longifolia Jack enhances sexual motivation in middle-aged male mice.
J Basic Clin Physiol Pharmacol. 2003;14(3):301-8.

Abstract
School of Pharmaceutical Sciences, University Science Malaysia, Minden, Penang, Malaysia.

Eurycoma longifolia Jack was investigated for sexual motivation activity in adult, middle-aged male mice and in retired breeders, using the modified open field and the modified runway choice methods. Each mouse received 500 mg/kg of one of 4 fractions of E. longifolia Jack, viz. chloroform, methanol, butanol, and water, whereas the mice in the control and yohimbine groups received 3 ml/kg of normal saline and 30 mg/kg of yohimbine daily respectively for 10 d. The results show a transient increase in the percentage of male mice responding to the right choice after chronic consumption of the fractions with 50 percent of the adult middle-aged male mice treated with E. longifolia Jack and yohimbine scoring the right choice after 8 and 5 days post-treatment respectively. In conclusion, this study has shown that E. longifolia Jack continues to enhance sexual motivation in adult, middle-aged male mice and in retired breeders.

To retrieve the full report go to:  http://www.ncbi.nlm.nih.gov/pubmed/14964739


Jack. Ang HH, Ikeda S, Gan EK
Evaluation of the potency activity of aphrodisiac in Eurycoma longifolia
Phytother Res 2001 Aug; 15(5):435-6

Abstract
School of Pharmaceutical Sciences, University Science Malaysia, Minden, 11800, Penang, Malaysia

The butanol, methanol, water and chloroform extracts of the roots of Eurycoma longifolia Jack were studied using various tests of potency of treated male rats. The results showed that E. longifolia produced a dose-dependent, recurrent and significant increase in the episodes of penile reflexes as evidenced by increases in quick flips, long flips and erections of the treated male rats during the 30 min observation period. These results provide further evidence that E. longifolia increases the aphrodisiac potency activity in treated animals. Copyright 2001 John Wiley & Sons, Ltd.

To retrieve the full report go to:  http://www.ncbi.nlm.nih.gov/pubmed/11507738

Niacin Rescources

A list of detailed niacin studies can be found at: www.oralchelation.com/technical/niacin1.htm

Saw Palmetto Studies – downloadable

Our Products